Abstract Background Several inflammatory molecules participate in the immune response to malaria.Interleukin (IL)-18 is an inflammatory cytokine activated by NLRP3 inflammasomes.In clinical falciparum malaria, with and without HIV co-infection, data on IL-18 and in particular on its binding protein, IL-18bp, is scarce.Methods Clinical data and bloo
Computational methods for 16S metabarcoding studies using Nanopore sequencing data
Assessment of bacterial diversity nyx 22 brush through sequencing of 16S ribosomal RNA (16S rRNA) genes has been an approach widely used in environmental microbiology, particularly since the advent of high-throughput sequencing technologies.An additional innovation introduced by these technologies was the need of developing new strategies to manage
Evaluating an internet-delivered fear conditioning and extinction protocol using response times and affective ratings
Abstract Pavlovian fear conditioning is widely used to study mechanisms of fear learning, but high-throughput studies are hampered by the labor-intensive nature of examining participants in the lab.To circumvent this bottle-neck, fear conditioning tasks have been developed for remote delivery.Previous studies have examined remotely delivered fear c
Predicting hepatic failure with a new diagnostic technique by preoperative liver scintigraphy and computed tomography: a pilot study in 123 patients undergoing liver resection
Abstract Background A novel index, total liver LU15, has been identified as a surrogate marker for liver function.We evaluated the ability of preoperative remnant liver LU15 values to predict postoperative hepatic failure.Methods Preoperative risk factors for postoperative hepatic failure and remnant liver LU15 were evaluated in 123 patients underg